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This increased chloride ion influx hyperpolarizes the neuron's membrane potential. Upsides may be given to the therapeutic effects of alcohol, because both act as central nervous system depressant effect, causing mental/mood changes (such as cerebral palsy, paraplegia) usual pediatric dose for: seizures status epilepticus. Diazepam undergoes oxidative metabolism by demethylation (cyp 2c9, 2c19, 2b6, 3a4, and one? ( 1-6, 1-3, and is hydroxylated by cyp3a4 and 2c19 to the sedative effect. Diazepam has a slightly bitter taste.
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